Launch of the 2014 call for research proposals of the ELA Foundation



Written on Monday 7 April 2014

The ELA Research Foundation invites the international scientific community to submit innovative research applications in the field of genetic leukodystrophies and myelin repair. It is a way to promote a better understanding of leukodystrophies and the development of promising therapies.

 

 

 

Application submission deadline : June 2, 2014 (5PM, French time)

 

ELIGIBLE RESEARCH TOPICS

Well characterized leukodystrophies*

  • Preclinical & clinical studies testing gene, cell, enzyme or pharmacological therapies
  • Improved animal and cell models close to the human disease phenotype

Studies on pathogenesis mechanisms in leukodystrophies will be considered only if they have a clear objective towards the development of therapeutic strategies (identifying novel and druggable targets, development & characterization of experimental models allowing drug screening), and/or are of exceptional and innovative quality, and are fundable for a maximum of 2 years.

Poorly characterized leukodystrophies**

  • High-throughput screening for identification of biomarkers
  • Study of natural history using clinical databases and biobanks
  • Development of animal or cell models
  • Studies of pathogenic mechanisms and therapeutic approaches

Myelin repair

  • Therapies promoting remyelination in preclinical animal models of leukodystrophy

*Such as adrenoleukodystrophy/adrenomyeloneuropathy, metachromatic leukodystrophy, Krabbe disease, Canavan disease, Pelizaeus-Merzbacher disease
**Those with recently identified genes or with genes of unknown functions

 

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